Speaker
Description
Introduction by Mikhail Zubkov
Elevated brain iron levels are a hallmark of neurodegenerative diseases, includingAlzheimer’s and Parkinson’s. Although MRI provides a non-invasive means ofassessing brain iron using contrasts like quantitative susceptibility and transverserelaxation rates, these biomarkers often lack specificity. To address this, Evgeniya’swork integrated multiple iron-sensitive MRI parameters with biophysical models and3D quantitative histology to understand iron-induced contrast mechanisms. Thisapproach enables the development of cell-specific MRI biomarkers. For this talk,Evgeniya will discuss a key application of this work: mapping density and iron loadof dopaminergic neurons for the early detection of Parkinson's disease.
