Seminars

Evgenios Kornaropoulos (CRC): "From Diffusion to Magnetization Transfer: A Progressive Journey Through Tissue Microstructure"

Name: Evgenios Kornaropoulos (CRC): "From Diffusion to Magnetization Transfer: A Progressive Journey Through Tissue Microstructure"
Start: 2025-03-31T14:00:00+02:00
End: 2025-03-31T15:00:00+02:00
Location: CRC

Monday 31 Mar 2025, 14:00 → 15:00 Europe/Brussels

B-30/0-000 - Big meeting room (CRC)

B-30/0-000 - Big meeting room

CRC

Description

Abstract: My presentation focuses on microstructural imaging using ultra-high-field MRI, and it is organized into two parts: the inhomogeneous magnetization transfer (ihMT) approach and the diffusion-weighted imaging (DWI) approach. In the first part, I will present my postdoctoral research at Aix-Marseille University, and I will demonstrate how evaluating the magnetization exchange between free water molecules and macromolecules can serve as a marker for demyelination. In the second part, I will share insights from my work on traumatic brain injury, a project conducted in collaboration with the University of Cambridge and Lund University. Finally, I will conclude with a brief overview of my ongoing efforts to develop a proxy measure for the glymphatic system's role in TBI using DWI.

Bio:I am an interdisciplinary neuroimaging researcher with master’s-level training in electrical and computer engineering (Democritus University of Thrace, Greece) and biomedical engineering (Delft University of Technology, The Netherlands), as well as a PhD in Computer Vision applied to Medical Radiation Physics (University of Paris-Saclay, France). I leverage my engineering and medical radiation physics background to develop and optimize MRI and other imaging techniques for clinical neuroscience, particularly for studying traumatic brain injury (TBI) and its connection to neurodegeneration. Over my postdoctoral tenures at the University of Cambridge (UK), Lund University (Sweden), and Aix-Marseille University (France), I have focused on diffusion-weighted imaging and inhomogeneous magnetization transfer imaging as two indirect but informative probes of tissue microstructure. The former aggregates molecular microscopic diffusion behavior into a macroscopic measurement, while the latter aggregates molecular-level magnetization exchange into an observable signal. Recently, I have also begun examining the role the glymphatic system plays in TBI progression.